Doctors Publications

09Oct

The strategic use of antiretrovirals to prevent HIV infection

There is a clear convergence toward an overarching strategic use of antiretroviral drugs to prevent human immunodeficiency virus (HIV) infection. Four interventions—immediate antiretroviral therapy (ART) for the infected partner in a serodiscordant couple, preexposure prophylaxis (PrEP), prevention of mother-to-child transmission (PMTCT), and postexposure prophylaxis (PEP)—are all strongly recommended by the World Health Organization as effective ways to prevent HIV infection. For HIV-infected individuals, ART to protect an HIV-uninfected partner and PMTCT are both part of an expanding list of recommendations for starting ART immediately to both treat and prevent HIV infection. For HIV-uninfected individuals, PrEP and PEP are increasingly being seen as related interventions, and there are compelling reasons to consider the provision of PEP as a potential gateway to PrEP.

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Mother-to-child transmission of HIV

The transmission of HIV from an HIV-positive mother to her child during pregnancy, labour, delivery or breastfeeding is called mother-to-child transmission. In the absence of any interventions transmission rates range from 15-45%. This rate can be reduced to levels below 5% with effective interventions. The global community has committed itself to accelerate progress for the prevention of mother-to-child HIV transmission (PMTCT) through an initiative with the goal to eliminate new paediatric HIV infections by 2015 and improve maternal, newborn and child survival and health in the context of HIV.

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02Oct

Sleeping on the job? Managing fatigue in the workplace

We all know that tiredness can make us grouchy and slow to react… but did you know it could also put your life at risk? Back in 2012, a well-reported French survey found that sleepiness behind the wheel is almost as bad as drinking and driving, and that drivers who were either drunk or sleepy were at least twice as likely to be responsible for a vehicle accident compared to their well-rested or sober counterparts. What is less well publicised, however, is the role fatigue can play on other types of accidents – particularly in the workplace. In this short post we look at the risks posed by sleepy workers, as well as considering the steps we can take to ensure they don’t come to, or cause any, harm.

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